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December, 2016:

Backup iPhone to External Hard Disk for Windows Based

The original location of the Backups is in a folder called MobileSync

This folder is located in: C:\Users\*USERNAME*\AppData\Roaming\Apple Computer\MobileSync\Backup

And to do move this folder’s location, you will have to:

Copy the folder to the new location (for example at the root of an external hard disk drive (HDD)
Go to the orinal folder location C:\Users\*USERNAME*\AppData\Roaming\Apple Computer\MobileSync\
Delete the folder “Backup” within or rename it “BackupOld” to keep it
Create new location at your external hard disk, ie D:\iTunes Backup
Press Shift+Right Click to open a Command window from that location
Type the following command
mklink /J “%APPDATA%\Apple Computer\MobileSync\Backup” “:\iTunes Backup”

Close Command prompt
Launch a backup, see if it has been properly located and iTunes sees is as the latest
Voilà, saving precious disk space on Windows is easy!